Mexico City, MexicoSantiago

Flights from Mexico City to Santiago

Nonstop flights from Mexico City (MEX) to Santiago (SCL) take about 8h 45m (6,596 km). Aeromexico, LATAM Airlines Group and Wamos Air fly it. Lowest fare seen: $581 one-way, nonstop (22 Oct 2026).

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When you land in Santiago

The airport transfer and the few things worth sorting before you fly.

Airport transfer

SCL → Santiago, booked before you fly

A private driver meets you in arrivals at a price agreed when you book. Book with Welcome Pickups.

See transfer prices
A stunning aerial view of Chapultepec Park with cityscape and mountains in the background. — lounges at Mexico City AirportMexico City Airport · 9 lounges
Before you flyAirport lounges at Mexico City →
Trains, buses and taxi faresSCL to Santiago: getting into town →Early arrival or late flightLuggage storage in Santiago →9 drop-off points, from $3.90

Find hotels in Santiago

Hotels, hostels & more · Expedia

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Airlines flying Mexico City to Santiago

Carriers on MEX–SCL according to our route data and nonstop fares seen as of 22 Oct 2026. Not a complete list.

✈ Aeromexicononstop fare seen✈ LATAM Airlines Groupnonstop fare seen✈ Wamos Airnonstop fare seen

Mexico City to Santiago fares by month

Cheapest month seen for a nonstop flight: Nov 2026, from $581 one-way. With stops: Oct 2026, from $314. Lowest one-way fares seen for departures in each month, read 22 Oct 2026.

DepartingNonstop fromCheaper with stops
Oct 2026$61029 Oct 2026 · LATAM Airlines Group$314 · 1 stop29 Oct 2026
Nov 2026$58124 Nov 2026 · Aeromexico$387 · 3 stops24 Nov 2026
Dec 2026$6131 Dec 2026 · Aeromexico$421 · 1 stop1 Dec 2026
Feb 2027$82625 Feb 2027 · Aeromexico$466 · 2 stops25 Feb 2027
Jul 2027$72315 Jul 2027 · LATAM Airlines Group$571 · 2 stops15 Jul 2027 · Aeromexico

When to go for the lowest fare

The next few weeks were the cheapest to fly: from $314 in October 2026, against $421 at best later on.

Nonstop or with a stop

A connection undercut nonstop in 5 of 5 months with both fares.

From Travelpayouts flight-search data, city to city (Mexico City to Santiago, any airport), USD, read 22 Oct 2026. These are fares that were on sale, not a guarantee of today's price; an airline is named only where we know it flies this route.

More for this trip

Frequently asked questions — Mexico City to Santiago flights

How long is the flight from Mexico City to Santiago?
A nonstop flight from Mexico City (MEX) to Santiago (SCL) takes about 8h 45m, covering 6,596 km. That is an estimate from the distance — actual time varies with the airline, aircraft and winds, and connecting itineraries take longer.
How far is Mexico City from Santiago by air?
The great-circle distance between Mexico City Benito Juárez International Airport and Comodoro Arturo Merino Benítez International Airport is 6,596 km (4,099 miles), a long-haul route.
Which airlines fly from Mexico City to Santiago?
Airlines with flights or nonstop fares on the MEX–SCL route include Aeromexico, LATAM Airlines Group and Wamos Air. This is not a complete list — schedules change by season, so check the current options before booking.
How much does a flight from Mexico City to Santiago cost?
The lowest one-way fare seen recently on MEX–SCL was $581 USD with Aeromexico (nonstop), departing 24 Nov 2026, found in fare searches as of 22 Oct 2026. Fares change constantly and depend on the date, so check the current price before booking.
What is the cheapest month to fly from Mexico City to Santiago?
In fares seen on 22 Oct 2026, departures in October 2026 were cheapest, from $314 one-way, against $571 for July 2027, the dearest month. Fares change daily, so check your own dates.
Is it cheaper to fly nonstop or with a stop from Mexico City to Santiago?
In the fares we saw (22 Oct 2026), connecting was cheaper: from $398 with one stop against $581 nonstop, a saving of $183. Nonstop saves the connection time.
Do I need a visa to travel from Mexico to Santiago?
It depends on your passport. Some nationalities can enter Santiago visa-free or get a visa on arrival; others must apply in advance. Use AirConnect's Visa Checker to see the rules for your passport.

Sources: fares from Travelpayouts flight-search data, seen 22 Oct 2026; airlines from each carrier's published network and nonstop fares on sale; distance from OurAirports coordinates; flight time estimated from distance. Fares change daily.

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